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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIER1
All Species:
17.88
Human Site:
S146
Identified Species:
43.7
UniProt:
Q8N108
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N108
NP_001071169.1
536
60654
S146
E
E
N
I
K
D
S
S
G
Q
E
D
E
T
Q
Chimpanzee
Pan troglodytes
XP_001142293
550
61391
E155
T
A
C
D
G
D
K
E
S
E
V
E
D
V
E
Rhesus Macaque
Macaca mulatta
XP_001099786
550
61404
L144
S
D
F
F
P
R
P
L
R
S
N
T
T
C
D
Dog
Lupus familis
XP_864849
512
58177
S122
E
E
N
I
K
D
S
S
G
Q
E
D
E
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5UAK0
556
62962
S166
E
E
N
I
K
D
S
S
G
Q
E
D
E
T
Q
Rat
Rattus norvegicus
NP_001124484
512
57956
S122
E
E
N
I
K
D
S
S
G
Q
E
D
E
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519600
364
41076
Chicken
Gallus gallus
Q5ZKT9
513
58071
S124
E
E
T
I
K
D
S
S
G
Q
E
D
D
T
Q
Frog
Xenopus laevis
Q7T105
495
56289
D117
K
D
S
S
G
Q
E
D
E
T
Q
S
S
N
D
Zebra Danio
Brachydanio rerio
XP_694533
494
55652
G117
L
K
K
R
Q
E
D
G
A
K
V
S
T
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
41.6
92.1
N.A.
90.1
90.1
N.A.
55.5
82.4
70.3
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57
57.2
94.4
N.A.
93.1
93.2
N.A.
61.1
88.9
79.8
62.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
0
86.6
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
6.6
100
N.A.
100
100
N.A.
0
93.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
20
0
10
0
60
10
10
0
0
0
50
20
0
20
% D
% Glu:
50
50
0
0
0
10
10
10
10
10
50
10
40
0
10
% E
% Phe:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
20
0
0
10
50
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
10
10
0
50
0
10
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
40
0
0
0
0
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
50
10
0
0
0
50
% Q
% Arg:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
0
0
50
50
10
10
0
20
10
0
0
% S
% Thr:
10
0
10
0
0
0
0
0
0
10
0
10
20
50
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
20
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _